Acute and SubAcute Toxicological Assessment of the ...
Jul 03, 2009· Acute toxicological experiments. Experiments to determine the oral median lethal dose (LD 50) of the aqueous seed extract of P. americana were carried out by using the method described by Miller and Tainter (1944). Six groups of male rats comprising of 4 rats per group were given the vehicle for extract reconstitution (control), 2, 4, 6, 8, 10 g/kg of the extract using an orogastric tube (CU ...